PAEA Surgery End Of Rotation (EOR) Practice Exam

What are the most common sites of metastasis for lung cancer?

1. Bone, liver, adrenals, kidney

2. Brain, pancreas, skin, heart

3. Muscle, spleen, stomach, bladder

4. Intestines, pancreas, lymph nodes, uterus

The correct answer is: Bone, liver, adrenals, kidney

The most common sites of metastasis for lung cancer include the bone, liver, adrenal glands, and kidney. This is due to the vascular and lymphatic connections of the lungs, which facilitate the spread of cancer cells. The bones can be particularly affected because they are highly vascularized areas, and lung cancer commonly spreads to the spine, ribs, and pelvis, leading to significant pain and other complications. Similarly, the liver serves as a common site for metastasis due to its extensive blood supply and role in filtering blood from the systemic circulation. Adrenal glands are often involved as well, given their proximity and shared blood supply with the lungs. Lastly, while metastasis to the kidney can occur, it is less frequent, but still considered among the common sites. The other groups listed in the options do not typically represent common metastatic sites for lung cancer, as they involve organs or tissues that are either less frequently affected or not directly aligned with the common pathways of cancer spread associated with lung malignancies. Understanding these pathways allows healthcare professionals to monitor for potential complications and tailor management for affected patients.